Asupan gula, lemak trans, dan asam lemak jenuh dari kopi instan bisa membuat kadar kolesterol jahat di tubuh meningkat. Biasanya, ketiga kandungan ini lebih cenderung mengikat zat besi yang berasal dari sumber zat besi nabati Mineral dalam kopi mempengaruhi penyerapan zat besi dalam tubuh. Serta mengurangi kemampuan ginjal untuk mempertahankan
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